Microsieves

Microsieves

Microsieves are microfiltration membranes with well-defined pores with, depending on the application, pore sizes in the range of 0.1 to 20 µm. A microsieve is composed of a rigid silicon support with on top a thin silicon nitride membrane (0.5 to 5 µm). Due to the high pore density, uniform pore size distribution and high aspect ratio (pore size versus membrane thickness) microsieves combine excellent size selective filtration with enhanced filter efficiencies at low flow resistance.

Hence, microsieves are applied in food industry, biotechnology and pharmaceutics, for instance, in beer or dairy filtration to remove bacteria, spores and yeast, microbial diagnostics of drinking water, waste water and blood samples, and production of well-defined functional emulsions and microspheres.

In many of these applications biofouling, i.e. non-specific adsorption of biomolecules, is a critical issue. Accordingly, modification of the microsieve surface with a stable biofouling molecular coating considerably improves microsieve performance. In addition, for microbial diagnostics microsieves can be functionalized with biofouling coatings with incorporated receptor sites for selective recognition of proteins and bacteria.     


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